As in the past, a wide range of topics—from genomics technologies and applications to analysis strategies and tools—will be covered during the 2026 meeting. Specific themes and focus areas for our 20th Anniversary meeting are the following:
Achievements in human genomics (research and clinical applications, oncology, inherited disease)
New frontiers (use of AI in genomics, multi-omics, genomics in space, consumer genomics)
Our interactions with the microbial world (microbiomes, metagenomics, infectious disease and biosurveillance)
An overview of the agenda for the 20th Annual SFA²F Meeting is given below. A more detailed summary will be available in due course.
4.00 PM - 7.00 PM: Registration desk open
Theme: Advances in Human Genetics
7:00 AM - 8.30 AM: Registration and breakfast
8.30 AM - 8.45 AM: Opening remarks
Keynote address:
Adam Phillippy, Ph.D., Director, Center for Genomics and Data Science Research, NHGRI, National Institutes of Health
Complete, T2T genomes as a foundation for predictive genomics
Panel discussion: NGS technology updates
Rest of day: Invited speakers, scientific and vendor talks
Evening: Meet-and-greet social with food, drinks and poster session
Theme: AI in genomics
7:30 AM - 8.30 AM: Breakfast
8.30 AM - 8.45 AM: Opening remarks
Keynote address:
Bruce Wittmann, Ph.D., Senior Applied Scientist, Office of the Chief Scientific Officer, Microsoft
DNA synthesis screening and AI: challenges and remedies
Panel discussion: AI in genomics
Rest of day: Invited speakers, scientific and vendor talks
Evening: Dinner on your own
Theme: New Frontiers
7:30 AM - 8.30 AM: Breakfast
8.30 AM - 8.45 AM: Opening remarks
Panel discussion: Space omics
Rest of day: Keynote address, invited speakers, scientific talks
Evening: 20th Anniversary Dinner Party
Sr Director and Institute Scientist,
Broad Institute;
Chair and CSO, Broad Clinical Labs
From discovery to translation—
a reflection on two decades of genomics
Director of Software Engineering and Programming, Human Genome Sequencing Center, Baylor College of Medicine
Applied AI for genomics:
lessons from real-world pipelines
Director, Center for Genomics and
Data Science Research, NHGRI, National Institutes of Health
Complete, T2T genomes as a foundation for predictive genomics
“I recall, with fondness, the first time I attended SFAF in 2010! I am delighted to be coming back 15 years later to reflect on the successes and challenges in our field of science.”
> Niall Lennon, invited speaker, 20th annual SFA²F meeting
Program Manager (retired),
Office of Biological and
Environmental Research
Reflections on the HGP
a quarter of a century later
Assistant Professor,
Duke University
The power of many: bridging the molecular and repertoire scales of immune protection
Adjunct Professor,
Dept. of Neuroscience, NYU Grossman
School of Medicine
All about the
Human Genome Project
“The SFAF series of meetings were key to laying the groundwork—first for finishing the HGP and then for enabling the critically important work of turning HGP data (the sequence) into useable information and the (still unfinished) work of beneficial knowledge.”
> Dan Drell, invited speaker, 20th annual SFA²F meeting
Senior Applied Scientist,
Office of the Chief Scientific Officer,
Microsoft
DNA synthesis screening and AI: challenges and remedies
Associate Professor,
Human Genome Sequencing Center,
Baylor College of Medicine
Decoding spaceflight biology
through multi-omics profiling
Ph.D. student,
MIT
BoltzGen: toward universal
binder design
“It is important that tool users and developers consider dual-use nature of advances in biotechnology. While the number of potential beneficial applications dramatically outweigh the number of malicious ones, we must work as a community to minimize any possible misuse. SFAF provides a forum for both spreading awareness of this duality and ensuring that biotechnological advancement is used solely for good.”
> Bruce Wittmann, invited speaker, 20th annual SFA²F meeting
“On SFA²F’s 20th anniversary, we’re excited to show how real-time transcriptomics can move from the lab into the field—because this meeting has always been where practical, next-step genomics gets shaped through honest technical conversations and cross-sector collaboration.”
> Max Perelman and Jesse van Westrienen, invited speakers, 20th annual SFA²F meeting